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Immune Responses and Therapeutics of Inflammatory Bowel Disease

Immune Responses and Therapeutics of Inflammatory Bowel Disease
Author : Salman Assad
Publisher : Lulu.com
Total Pages : 56
Release : 2018-02-09
ISBN 10 : 9781387582297
ISBN 13 : 1387582291
Language : EN, FR, DE, ES & NL
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Immune Responses and Therapeutics of Inflammatory Bowel Disease Book Description:

Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal tract associated with an imbalance of the intestinal microbiota. Crohn's disease (CD) and ulcerative colitis (UC) are the most widely known types of IBD and have been the focus of attention due to their increasing incidence. Recent studies have pointed out genes associated with IBD susceptibility that, together with environmental factors, may contribute to the outcome of the disease. In ulcerative colitis, there are several therapies available, depending on the stage of the disease. Aminosalicylates, corticosteroids, and cyclosporine are used to treat mild, moderate, and severe disease, respectively. Nowadays, advances in treatments for IBD have included biological therapies, based mainly on monoclonal antibodies or fusion proteins, such as anti-TNF drugs.

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